SUBJECT:  ANGELMAN SYNDROME
                Request for Research Proposals
                Deadline for Receipt: October 1, 2000

The Angelman Syndrome Foundation, USA announces the availability of $100,000 to be awarded in support of research on Angelman syndrome. All areas of biomedical and behavioral research involving AS will be considered. The Angelman Syndrome Foundation will be flexible regarding the number of awards made and the amount of funding for each.

Applicants should follow these general guidelines:

A one-page summary abstract of proposed research.

The main body of the proposal should not exceed 6 pages and should include identification of the primary investigator, a summary of background, hypothesis, methods, significance of the proposed research and time frame for completion.

A one-page budget summary and justification. No indirect costs will be allowed.

A curriculum vitae of the principal investigator(s).

Letters of support/collaboration where necessary.

Proposals dealing with human or animal subjects must conform to usual review by an Institutional Review Board (IRB); a copy of approval must be provided before funding is released.

A cover letter and ten copies of the above should be submitted to:

Scientific Advisory Committee
Angelman Syndrome Foundation, USA
c/o Prof. Daniel F. Harvey, Ph.D.
Department of Chemistry and Biochemistry
University of California, San Diego
La Jolla, CA 92093-0358
Proposals will be reviewed by the Scientific Advisory Committee of the Angelman Syndrome Foundation.

Questions about this announcement should be directed to:

Prof. Daniel F. Harvey, Ph.D.
Chair, ASF Scientific Advisory Committee
Department of Chemistry and Biochemistry
University of California, San Diego
La Jolla, CA 92093-0358
Phone: 858-534-0388
Fax: 858-534-5383
Email: dharvey@ucsd.edu

                                                Marsha A. Chandler
                                                Senior Vice Chancellor