SUBJECT:

William K. Warren Medical Research Center for Celiac

Disease Pilot Feasibility Award Program The Wm. K. Warren Celiac Disease Research Center is pleased to announce a program to support new research initiatives in Celiac Disease.

Scope

The primary goal of the program is to provide Awardees with funds to develop new Celiac Disease related research initiatives that will lead to submission of competitive grant applications.

Mechanism of Support

Two or more applications of up to $25,000 a year will be made to eligible applicants. Awards are intended to support preliminary data collection that will be used in applications for future research grants related to Celiac Disease. A second year of funding may be requested by submission of a competitive renewal application.

Eligibility

Investigators must meet one of the following criteria:

1. New Investigators. Applicants cannot be a principal investigator on a NIH R01 or P01 grant.

Trainees can be supported by an NRSA individual award or supported by an institutional training grant (T32), if they are: (a) in their last year of training; (b) have had at least two years of laboratory research experience at the start of this award, or (c) have suitable expertise and independence to design and carry out planned experiments. Trainees will need a letter of commitment from a senior scientist to sponsor the project. Funds cannot be used to supplement stipends, but can be used for supplies, technical support, and miscellaneous expenses.

2. Established Funded Investigators. Applicants who do not currently conduct research on Celiac Disease, but wish to test the applicability of their expertise or the feasibility of a new or innovative idea to this problem.

General Instructions

Qualified applicants must submit a Letter of Intent by November 1, 2005, to the address listed below, it should include the following:

* Letter containing 1-2 page description of the project’s aims and method of approach.

* NIH-format Biographical Sketch (4 page limit).

Send Letters of Intent to:

Wm. K. Warren Medical Research Center for Celiac Disease
Pilot Feasibility Award Program
Attn: Roslyn Lara
University of California, San Diego
Department of Medicine
9500 Gilman Drive (MTF/412)
La Jolla, CA 92093-0623

After an initial screening, requests will be sent to investigators to submit a complete proposal.

Application Requirements

Font

* 12 point type

* Use black ink for clear copies

Page Margins

* 1-inch margins

Application Characteristics

* Applicants may request a project period of up to two years. The budget should reflect direct costs only (no indirect costs allowed).

* Second year contingent on competing continuation application.

* Support may not be used for thesis or dissertation research.

* Research Plan (Specific Aims, Relevance, Background, Preliminary Studies, and Research Design and Methods) may not exceed 5 pages.

* A progress report is not needed, unless proposal is a competing continuation application.

* Appendix may include only original, glossy photographs or color images of gels, micrographs, etc. provided that a photocopy (may be reduced in size) is also within the page limits of the research plan. No publications or other printed material, with the exception of preprinted questionnaires or surveys, may be included in the appendix.

Proposal Checklist:

___ Eligibility category of the investigator
___ Abstract
___ NIH-format BioSketch (4-page limit)
___ Budget (salary support for principal investigator)
___ Budget Justification
___ NIH-format Other Support page
___ NIH format Resources page
___ Research Proposal (not to exceed 5 pages, single spaced)

___ Specific Aims
___ Relevance to Celiac Disease
___ Background
___ Preliminary Data (if the proposal builds on previous results)
___ Research Plan (include a discussion of anticipate difficulties and alternative approaches
___ References (not included in 5-page limit)
___ Letter of Commitment by Senior Scientist
___ Electronic version of proposal

Application Receipt Date: Applications (original and 8 copies) must be received no later than December 15, 2005.

Direct inquiries to:

Roslyn Lara
Wm. K. Warren Medical Research Center for Celiac Disease
University of California, San Diego
Department of Medicine
9500 Gilman Drive (MTF/412)
La Jolla, CA 92093-0623
Phone: 858-534-4622/Email: rlara@ucsd.edu

Send proposals to: Original and 8 copies to:

Roslyn Lara
The Wm. K. Warren Medical Research Center for Celiac Disease
Pilot Feasibility Research Award
University of California, San Diego
Department of Medicine
9500 Gilman Drive (MTF/412)
La Jolla, CA 92093-0623

Edward W. Holmes, M.D. Vice Chancellor for Health Sciences